Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | FCER2 | P06734 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635949 | 0.89 | OPRM1 (0.41) | OPRD1OPRM1OPRK1MMP1FCER2 | |
| SCHEMBL17031988 | 0.84 | XIAP (0.39) | OPRD1OPRM1OPRK1MMP1FCER2 | |
| SCHEMBL18635686 | 0.84 | ELANE (0.45) | OPRD1OPRM1OPRK1ELANE | |
| SCHEMBL18635688 | 0.84 | ELANE (0.45) | OPRD1OPRM1OPRK1ELANE | |
| SCHEMBL17031987 | 0.84 | ELANE (0.45) | OPRD1OPRM1OPRK1ELANE | |
| SCHEMBL17024615 | 0.81 | OPRM1 (0.44) | OPRD1OPRM1OPRK1BCL2 | |
| SCHEMBL17024720 | 0.81 | OPRM1 (0.44) | OPRD1OPRM1OPRK1BCL2 | |
| SCHEMBL17024517 | 0.77 | XIAP (0.40) | OPRD1OPRM1OPRK1MMP1FCER2 | |
| SCHEMBL17024515 | 0.77 | XIAP (0.40) | OPRD1OPRM1OPRK1MMP1FCER2 | |
| SCHEMBL9543837 | 0.75 | ELANE (0.47) | OPRD1OPRM1OPRK1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903998-B1 | IAP ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-15 | — | — | EP | disclosed |