Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | FCER2 | P06734 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635844 | 0.89 | OPRD1 (0.38) | OPRM1OPRD1OPRK1TACR1XIAP | |
| SCHEMBL18636117 | 0.82 | ELANE (0.47) | OPRM1OPRD1OPRK1ELANENAMPT | |
| SCHEMBL19289877 | 0.78 | BIRC2 (0.39) | XIAPELANEBIRC3BIRC2 | |
| SCHEMBL18435537 | 0.78 | BIRC2 (0.39) | XIAPELANEBIRC3BIRC2 | |
| SCHEMBL18635996 | 0.76 | XIAP (0.48) | TACR1XIAPBIRC3BIRC2ACE | |
| SCHEMBL18635814 | 0.76 | XIAP (0.52) | XIAPBIRC3BIRC2 | |
| SCHEMBL18635985 | 0.74 | XIAP (0.45) | XIAPBIRC3BIRC2 | |
| SCHEMBL18635839 | 0.74 | XIAP (0.45) | XIAPBIRC3BIRC2 | |
| SCHEMBL17031989 | 0.74 | XIAP (0.39) | XIAPELANEBIRC3BIRC2NAMPT | |
| SCHEMBL17031988 | 0.73 | XIAP (0.39) | OPRM1OPRD1OPRK1XIAPELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903998-B1 | IAP ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-15 | — | — | EP | disclosed |