Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855230 | 1.00 | TDP1 (0.38) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL18922358 | 0.87 | TDP1 (0.38) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL18879385 | 0.87 | TDP1 (0.34) | TDP1L3MBTL1NR1I2KCNA5KCNH2 | |
| SCHEMBL18922343 | 0.87 | TDP1 (0.38) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL19261329 | 0.85 | TDP1 (0.37) | TDP1L3MBTL1KCNA5KCNH2LMNA | |
| SCHEMBL19133214 | 0.85 | TDP1 (0.37) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL20626584 | 0.85 | TDP1 (0.39) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL19176519 | 0.81 | TDP1 (0.36) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL26169677 | 0.81 | CYSLTR2 (0.36) | TDP1L3MBTL1CYSLTR2CYSLTR1KCNA5 | |
| SCHEMBL18737292 | 0.81 | TDP1 (0.36) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023536-B2 | Suprametallogels and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170073311-A1 | SUPRAMETALLOGELS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023536-B2 | Suprametallogels and uses thereof | PDCD1LG2, PDCD2L, PYGL | TDP1 2137/4885L3MBTL1 513/4885NR1I2 2161/4885 |
| US-20170073311-A1 | SUPRAMETALLOGELS AND USES THEREOF | PDCD1LG2, PDCD2L, PYGL | TDP1 2137/4885L3MBTL1 513/4885NR1I2 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.