Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922343 | 1.00 | TDP1 (0.38) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL19133214 | 0.98 | TDP1 (0.37) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL20626584 | 0.98 | TDP1 (0.39) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL18635979 | 0.87 | TDP1 (0.38) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL18855230 | 0.87 | TDP1 (0.38) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL23869499 | 0.82 | TDP1 (0.37) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL20940171 | 0.82 | TDP1 (0.37) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL21142338 | 0.82 | TDP1 (0.37) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL20621443 | 0.82 | TDP1 (0.37) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 | |
| SCHEMBL22260423 | 0.80 | AOC1 (0.38) | TDP1L3MBTL1NR1I2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669032-B2 | Enhanced treatment regimens using mTOR inhibitors | INTELLIKINE LLC (US) | 2017-06-06 | — | — | US | disclosed |