SCHEMBL186382

SCHEMBL186382

O=[N+]([O-])c1nc2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 2/20 0.58
▸ MMP9 P14780 2/20 0.58
▸ MMP8 P22894 2/20 0.58
▸ MMP13 P45452 1/20 0.54
▸ NPC1 O15118 9/20 0.53
▸ RAB9A P51151 7/20 0.53
▸ ALDH1A1 P00352 7/20 0.52
▸ SMN1; SMN2 Q16637 5/20 0.52
▸ KDM4E B2RXH2 3/20 0.52
▸ TP53 P04637 2/20 0.52
▸ PKM P14618 2/20 0.52
▸ NPSR1 Q6W5P4 2/20 0.52
▸ ABCB11 O95342 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ MAPT P10636 6/20 0.50
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ GAA P10253 2/20 0.50
▸ LMNA P02545 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31251212 1.00 MMP2 (0.58) MMP2MMP9MMP8MMP13NPC1
Iodide SCHEMBL11500380 0.98 MMP2 (0.57) MMP2MMP9MMP8MMP13NPC1
SCHEMBL9483143 0.98 MMP2 (0.57) MMP2MMP9MMP8MMP13NPC1
SCHEMBL11508819 0.98 MMP2 (0.57) MMP2MMP9MMP8MMP13NPC1
Nitric Acid SCHEMBL28189835 0.94 MMP2 (0.54) MMP2MMP9MMP8MMP13NPC1
Propane SCHEMBL4508219 0.93 MMP2 (0.53) MMP2MMP9MMP8MMP13NPC1
Benzaldehyde SCHEMBL28118424 0.81 NPC1 (0.44) MMP2MMP9MMP8MMP13NPC1
SCHEMBL8874842 0.78 KMT2A (0.56) MMP2MMP9MMP8MMP13NPC1
SCHEMBL22975129 0.76 TNKS2 (0.61) NPC1RAB9AALDH1A1KDM4EPKM
SCHEMBL30852300 0.76 TNKS2 (0.61) NPC1RAB9AALDH1A1KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2621 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025243001-A1 COVALENT TAG UNIVERSITY OF DUNDEE (GB) 2025-11-27 — — WO claimed
US-20250277257-A1 HYBRIDIZATION COMPOSITIONS AND METHODS DAKO DENMARK APS (DK) 2025-09-04 — — US claimed
CN-119638632-A Nitro-imidazole and amino preparation method of benzimidazole compound 烟台海川化学制品有限公司 2025-03-18 — — CN claimed
CN-118950094-A Acid-resistant catalyst and preparation method thereof 江苏扬农化工集团有限公司 2024-11-15 — — CN claimed
CN-118619886-B Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof 山东齐氟新材料有限公司 2024-10-25 — — CN claimed
CN-118652479-A Degradable antibacterial hydrogel and preparation method thereof 江苏欧亚立日化有限公司 2024-09-17 — — CN claimed
CN-118619886-A Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof 山东齐氟新材料有限公司 2024-09-10 — — CN claimed
CN-117534620-A Preparation method of palladium-catalyzed hydrocarbon bond functionalized 2-trifluoromethyl benzimidazole compound 六盘水师范学院 2024-02-09 — — CN claimed
CN-109988794-B Method for synthesizing nitrobenzimidazole derivatives through enzyme catalysis in continuous flow reactor 浙江农林大学 2023-06-13 — — CN claimed
US-20230123029-A1 ZIF NANOPARTICLE CONTAINING TRI-LIGANDS, THE METHOD OF MANUFACTURING THE SAME, MIXED MATRIX MEMBRANE COMPRISING THE SAME AND METHOD OF SEPARATING GAS USING THE MEMBRANE SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (KR) 2023-04-20 — — US claimed
WO-2003050306-A1 HYBRIDIZATION PORTION CONTROL OLIGONUCLEOTIDE AND ITS USES SEEGENE, INC. (KR) 2003-06-19 — — WO claimed
WO-2003050305-A1 ANNEALING CONTROL PRIMER AND ITS USES SEEGENE, INC. (KR) 2003-06-19 — — WO claimed
EP-0670053-A1 SOLID ANTIFOGGANT AGENT AND SOLID SINGLE PART HIGH CONTRAST RAPID ACCESS DEVELOPER SUN CHEMICAL CORPORATION (US) 1995-09-06 — — EP claimed
WO-1994011783-A1 SOLID ANTIFOGGANT AGENT AND SOLID SINGLE PART HIGH CONTRAST RAPID ACCESS DEVELOPER SUN CHEMICAL CORPORATION (US) 1994-05-26 — — WO claimed
US-5272045-A Water soluble antifoggant for powder developer solutions SUN CHEMICAL CORPORATION (US) 1993-12-21 — — US claimed
EP-0448841-B1 PHOTOGRAPHIC MATERIALS CONTAINING ELECTRON ACCEPTING AGENTS AGFA-GEVAERT N.V. (BE) 1993-06-02 — — EP claimed
US-5198333-A Nitro-containing heterocyclic compoudns; positive or negative roomlight emulsions; graphic arts AGFA-GEVAERT, N.V. (BE) 1993-03-30 — — US claimed
EP-0448841-A1 Photographic materials containing electron accepting agents AGFA-GEVAERT N.V. (BE) 1991-10-02 — — EP claimed
US-4469780-A COMBINED DEVELOPMENT AND INTENSIFICATION BATH FUJI PHOTO FILM CO., LTD. (JP) 1984-09-04 — — US claimed
US-4121938-A Photographic material containing TiO2, soluble Cu(II) salt, and soluble silver salt and the use thereof in physical development FUJI PHOTO FILM CO., LTD. (JP) 1978-10-24 — — US claimed
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