Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252414 | 0.85 | MEN1 (0.66) | MEN1BLMKMT2ATHRBRECQL | |
| Tetramethylrhodamine SCHEMBL2054818 | 0.85 | MEN1 (0.71) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL11987803 | 0.84 | MEN1 (0.64) | MEN1BLMKMT2ATHRBRECQL | |
| Rhodamine Ii SCHEMBL30320900 | 0.82 | MEN1 (0.64) | MEN1BLMKMT2ATHRBRECQL | |
| Rhodamine Ii SCHEMBL12310066 | 0.82 | MEN1 (0.64) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14399201 | 0.82 | MEN1 (0.67) | MEN1BLMKMT2ATHRBRECQL | |
| Tetramethylrhodamine SCHEMBL29838750 | 0.82 | P2RY6 (0.67) | MEN1BLMKMT2ATHRBRECQL | |
| Tetramethylrhodamine SCHEMBL13815486 | 0.82 | P2RY6 (0.67) | MEN1BLMKMT2ATHRBRECQL | |
| Tetramethylrhodamine SCHEMBL30091907 | 0.81 | P2RY6 (0.66) | MEN1BLMKMT2ATHRBRECQL | |
| Tetramethylrhodamine SCHEMBL29587824 | 0.81 | P2RY6 (0.66) | MEN1BLMKMT2ATHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395358-B1 | Covalent tethering of functional groups to proteins | PROMEGA CORP (US) | 2017-03-29 | — | — | EP | disclosed |
| EP-3141905-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2017-03-15 | — | — | EP | disclosed |