Rhodamine Ii

Rhodamine Ii

SCHEMBL30320900

COC(=O)c1ccccc1-c1c2ccc(=[N+](C)C)cc-2oc2cc(N(C)C)ccc12

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.64
▸ THRB P10828 1/20 0.64
▸ RECQL P46063 1/20 0.64
▸ BLM P54132 1/20 0.64
▸ KMT2A Q03164 1/20 0.64
▸ TDP1 Q9NUW8 1/20 0.64
▸ P2RY6 Q15077 1/20 0.58
▸ ABCB1 P08183 2/20 0.57
▸ USP2 O75604 2/20 0.55
▸ CFTR P13569 1/20 0.55
▸ PAX8 Q06710 1/20 0.55
▸ ATM Q13315 1/20 0.55
▸ GOPC Q9HD26 1/20 0.55
▸ CA12 O43570 3/20 0.48
▸ CA1 P00915 3/20 0.48
▸ CA2 P00918 3/20 0.48
▸ CA9 Q16790 3/20 0.48
▸ ITPR1 Q14643 1/20 0.47
▸ CA14 Q9ULX7 1/20 0.43
▸ HTR3A P46098 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rhodamine Ii SCHEMBL12310066 1.00 MEN1 (0.64) MEN1THRBRECQLBLMKMT2A
Rhodamine Ii SCHEMBL29350990 0.96 MEN1 (0.60) MEN1THRBRECQLBLMKMT2A
SCHEMBL14046505 0.90 ABCB1 (0.55) MEN1THRBRECQLBLMKMT2A
SCHEMBL11987803 0.90 MEN1 (0.64) MEN1THRBRECQLBLMKMT2A
Rhodamine I SCHEMBL12056734 0.90 MEN1 (0.61) MEN1THRBRECQLBLMKMT2A
Rhodamine I SCHEMBL29438185 0.90 MEN1 (0.61) MEN1THRBRECQLBLMKMT2A
SCHEMBL18440187 0.89 MEN1 (0.58) MEN1THRBRECQLBLMKMT2A
Tetramethylrhodamine SCHEMBL2054818 0.89 MEN1 (0.71) MEN1THRBRECQLBLMKMT2A
SCHEMBL14399388 0.88 MEN1 (0.64) MEN1THRBRECQLBLMKMT2A
SCHEMBL14399201 0.88 MEN1 (0.67) MEN1THRBRECQLBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049349-A1 MATERIALS AND METHODS FOR SPATIAL TRANSCRIPTOMICS 10X GENOMICS, INC. (US) 2026-02-19 — — US disclosed
US-12435363-B1 Materials and methods for spatial transcriptomics 10X GENOMICS, INC. (US) 2025-10-07 — — US disclosed
US-20250270657-A1 Detection of Antibiotic Resistance Genes STRECK, INC. 2025-08-28 — — US disclosed
US-20250115628-A1 FLUORINATED FLUOROPHORES HOWARD HUGHES MEDICAL INSTITUTE 2025-04-10 — — US disclosed
CN-113196056-B Analysis 卢米瑞德思英国有限公司 2024-10-29 — — CN disclosed
US-11958976-B2 Photoactive fluorophores and methods of in vivo labeling HOWARD HUGHES MEDICAL INSTITUTE (US) 2024-04-16 — — US disclosed
US-20230095090-A1 PHOTOACTIVE FLUOROPHORES AND METHODS OF IN VIVO LABELING HOWARD HUGHES MEDICAL INSTITUTE 2023-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230095090-A1 PHOTOACTIVE FLUOROPHORES AND METHODS OF IN VIVO LABELING PDGFRA, FES, TIE1 MEN1 3151/4885THRB 2530/4885RECQL 4244/4885
US-11958976-B2 Photoactive fluorophores and methods of in vivo labeling PDGFRA, FES, TIE1 MEN1 3151/4885THRB 2530/4885RECQL 4244/4885
US-20250115628-A1 FLUORINATED FLUOROPHORES PFAS, FLI1, ARFGEF1 MEN1 835/4885THRB 4536/4885RECQL 2225/4885
US-20260049349-A1 MATERIALS AND METHODS FOR SPATIAL TRANSCRIPTOMICS METTL16, RNGTT, NSUN2 MEN1 4139/4885THRB 1523/4885RECQL 3752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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