Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730577 | 1.00 | HDAC2 (0.45) | HDAC2SLC18A3SIGMAR1SLC6A2ADRA1A | |
| SCHEMBL4194401 | 1.00 | HDAC2 (0.45) | HDAC2SLC18A3SIGMAR1SLC6A2ADRA1A | |
| SCHEMBL15730212 | 1.00 | HDAC2 (0.45) | HDAC2SLC18A3SIGMAR1SLC6A2ADRA1A | |
| SCHEMBL4207545 | 1.00 | HDAC2 (0.45) | HDAC2SLC18A3SIGMAR1SLC6A2ADRA1A | |
| SCHEMBL24477577 | 0.82 | SLC18A3 (0.45) | HDAC2SLC18A3SIGMAR1SLC6A2ADRA1A | |
| SCHEMBL11217932 | 0.82 | SLC18A3 (0.45) | HDAC2SLC18A3SIGMAR1SLC6A2ADRA1A | |
| SCHEMBL5011948 | 0.82 | SLC18A3 (0.55) | SLC18A3SIGMAR1SLC6A2ADRA1AHTR2B | |
| SCHEMBL31412629 | 0.80 | KDM1A (0.39) | SIGMAR1SLC6A2HTR2BSLC6A3PNMT | |
| Hydrochloric Acid SCHEMBL23123614 | 0.80 | SLC18A3 (0.44) | HDAC2SLC18A3SIGMAR1SLC6A2ADRA1A | |
| SCHEMBL768116 | 0.78 | SLC18A3 (0.45) | SLC18A3SIGMAR1SLC6A2ADRA1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724682-B2 | Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | FTH1, FLI1, FECH | HDAC2 507/4885SLC18A3 1168/4885SIGMAR1 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.