Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13314952 | 0.80 | MAPT (0.42) | SLC18A3MEN1KMT2AMAPTCYP2C19 | |
| SCHEMBL26938568 | 0.80 | MAPT (0.42) | SLC18A3MEN1KMT2AMAPTCYP2C19 | |
| SCHEMBL170815 | 0.79 | MEN1 (0.55) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL170738 | 0.79 | MEN1 (0.55) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL4207545 | 0.78 | HDAC2 (0.45) | SLC18A3SIGMAR1GAAMAPTAKR1C3 | |
| SCHEMBL18639712 | 0.78 | HDAC2 (0.45) | SLC18A3SIGMAR1GAAMAPTAKR1C3 | |
| SCHEMBL16510459 | 0.78 | CYP19A1 (0.35) | SLC18A3MEN1KMT2AMAPTLMNA | |
| SCHEMBL4194401 | 0.78 | HDAC2 (0.45) | SLC18A3SIGMAR1GAAMAPTAKR1C3 | |
| SCHEMBL15730212 | 0.78 | HDAC2 (0.45) | SLC18A3SIGMAR1GAAMAPTAKR1C3 | |
| SCHEMBL15730577 | 0.78 | HDAC2 (0.45) | SLC18A3SIGMAR1GAAMAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380314-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL R&D INVEST S A (PT) | 2022-12-01 | — | — | US | disclosed |
| US-20120071495-A1 | Treatment for Neurological and Mental Disorders | PSYCHOGENICS, INC. (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071495-A1 | Treatment for Neurological and Mental Disorders | PNMT, COMT, ACHE | SLC18A3 16/4885SIGMAR1 477/4885MEN1 2930/4885 |
| US-20220380314-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GBA1, GBA2, CLN6 | SLC18A3 2438/4885SIGMAR1 1641/4885MEN1 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.