Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NAT1 | P18440 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488876 | 0.68 | — | — | |
| SCHEMBL9209921 | 0.67 | MEN1 (0.34) | PIM1PIM3PIM2CYP1A2MEN1 | |
| SCHEMBL6745371 | 0.64 | ALDH1A1 (0.37) | PIM1PIM3PIM2CYP1A2HPGD | |
| SCHEMBL6836753 | 0.61 | AKT1 (0.42) | CYP1A2HPGDF3MEN1KMT2A | |
| Methylamine SCHEMBL28226585 | 0.61 | ALDH1A1 (0.35) | PIM1PIM3PIM2CYP1A2HPGD | |
| SCHEMBL28066368 | 0.60 | CYP1A2 (0.44) | PIM1PIM3PIM2CYP1A2HPGD | |
| SCHEMBL22471741 | 0.58 | CYP1A2 (0.34) | PIM1PIM3PIM2CYP1A2HPGD | |
| SCHEMBL25400816 | 0.58 | HPGD (0.48) | CYP1A2HPGDF3MEN1KMT2A | |
| SCHEMBL8466451 | 0.57 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL10632138 | 0.57 | CYP1A2 (0.52) | PIM1PIM3PIM2CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350035-A1 | COMBINATIONS OF MEDICAMENTS, CONTAINING PDE4-INHIBITORS AND EP4-RECEPTOR- ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-27 | — | — | US | claimed |
| CN-103788321-A | Short carbon chain fluorine polyurethane compound and water and oil repellent agent containing same | JINTEX CORP | 2014-05-14 | — | — | CN | claimed |
| EP-2555773-A1 | COMBINATIONS OF MEDICAMENTS, CONTAINING PDE4 INHIBITORS AND EP4 RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2013-02-13 | — | — | EP | claimed |
| EP-2400962-A1 | DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | claimed |
| EP-2400961-A1 | DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | claimed |
| WO-2011124524-A1 | COMBINATIONS OF MEDICAMENTS, CONTAINING PDE4 INHIBITORS AND EP4 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-13 | — | — | WO | claimed |
| WO-2010097332-A1 | DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | claimed |
| WO-2010097334-A1 | DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | claimed |
| EP-2205609-A2 | HETEROCYCLE-SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES | Boehringer Ingelheim International GmbH (DE) | 2010-07-14 | — | — | EP | claimed |
| WO-2009050242-A2 | HETEROCYCLE-SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | claimed |
| US-5159074-A | AMINOMETHANEPHOSPHONIC ACID ARYL ESTERS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | claimed |
| EP-3068823-B1 | FIBER-REINFORCED RESIN COMPOSITES AND METHODS OF MAKING THE SAME | BOEING CO (US) | 2019-07-24 | — | — | EP | disclosed |
| US-9012533-B2 | Fiber-reinforced resin composites and methods of making the same | THE BOEING COMPANY (US) | 2015-04-21 | — | — | US | disclosed |
| US-20150080494-A1 | Fiber-Reinforced Resin Composites and Methods of Making the Same | THE BOEING COMPANY (US) | 2015-03-19 | — | — | US | disclosed |
| US-20140350035-A1 | COMBINATIONS OF MEDICAMENTS, CONTAINING PDE4-INHIBITORS AND EP4-RECEPTOR- ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-27 | — | — | US | disclosed |
| US-6268072-B1 | AROMATIC RESIN | EASTMAN KODAK COMPANY | 2001-07-31 | — | — | US | disclosed |
| EP-1094101-A2 | Electroluminescent devices having naphthylanthracene-based polymers | EASTMAN KODAK COMPANY (US) | 2001-04-25 | — | — | EP | disclosed |
| EP-1088875-A2 | Electroluminescent devices having phenylanthracene-based polymers | EASTMAN KODAK COMPANY (US) | 2001-04-04 | — | — | EP | disclosed |
| CN-1112924-A | Novel thiazine or thiomorpholine derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 1995-12-06 | — | — | CN | disclosed |
| US-5159074-A | AMINOMETHANEPHOSPHONIC ACID ARYL ESTERS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350035-A1 | COMBINATIONS OF MEDICAMENTS, CONTAINING PDE4-INHIBITORS AND EP4-RECEPTOR- ANTAGONISTS | PTGER4, PTGER1, PDE4A | PIM1 2955/4885PIM3 3119/4885PIM2 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.