Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.60 |
| ▸ | ACE | P12821 | 4/20 | 0.59 |
| ▸ | CPA1 | P15085 | 4/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233444 | 1.00 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL233445 | 1.00 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL31174325 | 1.00 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL30735528 | 0.97 | MME (0.57) | MMEACECPA1ACE2 | |
| SCHEMBL29877007 | 0.95 | MME (0.55) | MMEACECPA1ACE2 | |
| SCHEMBL30400950 | 0.92 | MME (0.53) | MMEACECPA1ACE2 | |
| SCHEMBL29532187 | 0.92 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL2543451 | 0.92 | MME (0.57) | MMEACECPA1ACE2 | |
| SCHEMBL2543449 | 0.92 | MME (0.57) | MMEACECPA1ACE2 | |
| SCHEMBL30417812 | 0.91 | MME (0.59) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2143786-B1 | METHOD FOR PRODUCING DIPEPTIDE | KYOWA HAKKO BIO CO LTD (JP) | 2014-12-10 | — | — | EP | disclosed |
| US-8673590-B2 | Method for producing dipeptide | KYOWA HAKKO BIO CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| CN-101137368-B | Roflumilast for the treatment of diabetes | NYCOMED GMBH | 2012-05-16 | — | — | CN | disclosed |
| US-7939302-B2 | Process for producing dipeptides | KYOWA HAKKO BIO CO., LTD. (JP) | 2011-05-10 | — | — | US | disclosed |
| EP-1627884-B9 | Process for producing dipeptides | KYOWA HAKKO BIO CO LTD (JP) | 2010-10-20 | — | — | EP | disclosed |
| EP-1627884-B1 | Process for producing dipeptides | KYOWA HAKKO BIO CO LTD (JP) | 2010-07-21 | — | — | EP | disclosed |
| US-20100129867-A1 | METHOD FOR PRODUCING DIPEPTIDE | KYOWA HAKKO BIO CO., LTD. (JP) | 2010-05-27 | — | — | US | disclosed |
| CN-101715484-A | Method for producing dipeptide | KYOWA HAKKO KOGYO KK | 2010-05-26 | — | — | CN | disclosed |
| EP-2143786-A1 | METHOD FOR PRODUCING DIPEPTIDE | Kyowa Hakko Bio Co., Ltd. (JP) | 2010-01-13 | — | — | EP | disclosed |
| US-20090269806-A1 | PROCESS FOR PRODUCING DIPEPTIDES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
| US-7514243-B2 | Process for producing dipeptides | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-04-07 | — | — | US | disclosed |
| CN-1973042-A | Process for producing dipeptide | KYOWA HAKKO KOGYO KK (JP) | 2007-05-30 | — | — | CN | disclosed |
| EP-1627884-A1 | Process for producing dipeptides | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-02-22 | — | — | EP | disclosed |
| US-20050287626-A1 | Process for producing dipeptides | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-12-29 | — | — | US | disclosed |
| EP-0560989-B1 | ENTERAL PREPARATION FOR CANCER THERAPY | OTSUKA PHARMA CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5658895-A | SPRAY DRIED POWDER FROM OIL IN WATER EMULSION COMPRISING FREE AMINO ACIDS NUTRIENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0560989-A1 | ENTERAL PREPARATION FOR CANCER THERAPY | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1993-09-22 | — | — | EP | disclosed |