Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP7 | P09237 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433322 | 0.96 | MME (0.62) | MMELTA4H | |
| SCHEMBL29373701 | 0.93 | BACE1 (0.59) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL30735528 | 0.92 | MME (0.57) | MMEACECPA1ACE2 | |
| SCHEMBL31174325 | 0.92 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL233444 | 0.92 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL233445 | 0.92 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL1864186 | 0.92 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL29392023 | 0.91 | MME (0.61) | MMELTA4HMMP2MMP7MMP9 | |
| SCHEMBL30799773 | 0.91 | MME (0.58) | MMELTA4H | |
| SCHEMBL30051542 | 0.88 | MME (0.64) | MMELTA4HMMP2MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |