SCHEMBL30735528

SCHEMBL30735528

C[C@@H](O)[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MME P08473 6/20 0.57
ACE P12821 3/20 0.56
CPA1 P15085 3/20 0.56
ACE2 Q9BYF1 3/20 0.56
GNPAT O15228 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233445 0.97 MME (0.60) MMEACECPA1ACE2
SCHEMBL1864186 0.97 MME (0.60) MMEACECPA1ACE2
SCHEMBL31174325 0.97 MME (0.60) MMEACECPA1ACE2
SCHEMBL233444 0.97 MME (0.60) MMEACECPA1ACE2
SCHEMBL30417812 0.94 MME (0.59) MMEACECPA1ACE2
SCHEMBL30414144 0.94 MME (0.59) MMEACECPA1ACE2
SCHEMBL30400950 0.92 MME (0.53) MMEACECPA1ACE2
SCHEMBL30388715 0.92 MME (0.56) MMEACECPA1ACE2GNPAT
SCHEMBL29532187 0.92 MME (0.60) MMEACECPA1ACE2
SCHEMBL29877007 0.92 MME (0.55) MMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240033365-A1 POLY(2-OXAZOLINE)N-f-MLF DERIVATIVE CONJUGATES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE UNIVERSITY OF SOUTH ALABAMA (US) 2024-02-01 US claimed
US-20240024409-A1 N-f-MLF DERIVATIVES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE UNIVERSITY OF SOUTH ALABAMA (US) 2024-01-25 US claimed
US-20240033365-A1 POLY(2-OXAZOLINE)N-f-MLF DERIVATIVE CONJUGATES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE UNIVERSITY OF SOUTH ALABAMA (US) 2024-02-01 US disclosed
US-20240024409-A1 N-f-MLF DERIVATIVES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE UNIVERSITY OF SOUTH ALABAMA (US) 2024-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024409-A1 N-f-MLF DERIVATIVES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE FPR1, FPR2, FPR3 MME 49/4885ACE 2554/4885CPA1 677/4885
US-20240033365-A1 POLY(2-OXAZOLINE)N-f-MLF DERIVATIVE CONJUGATES THAT INHIBIT FORMYL PEPTIDE RECEPTORS FOR THE TREATMENT OF DISEASE FPR1, FPR2, FPR3 MME 200/4885ACE 4018/4885CPA1 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.