Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 3/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917474 | 0.77 | MAOB (0.47) | MAOBMAOAKDM4AKDM4BKDM4C | |
| SCHEMBL790991 | 0.76 | KDM1A (0.46) | MAOBMAOAKDM4AKDM4BKDM4C | |
| SCHEMBL14336784 | 0.73 | OPRL1 (0.46) | MAOBMAOAOPRL1KDM4AKDM4B | |
| SCHEMBL17552306 | 0.72 | MAOB (0.44) | MAOBMAOAOPRL1KDM4AKDM4B | |
| SCHEMBL10388101 | 0.72 | KDM4A (0.42) | MAOBMAOAOPRL1KDM4AKDM4B | |
| SCHEMBL28313136 | 0.70 | MAOB (0.42) | MAOBMAOAGRIN2DGRIN3BGRIN1 | |
| Vinyl Ether SCHEMBL15348796 | 0.68 | KDM4A (0.35) | KDM4AKDM4BKDM4CALOX5AP | |
| SCHEMBL10389478 | 0.68 | DPP4 (0.41) | OPRL1KDM4AKDM4BKDM4C | |
| SCHEMBL6053771 | 0.67 | GRIN2D (0.50) | MAOBMAOAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4640563 | 0.67 | KDM1A (0.43) | OPRL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3349853-A1 | PRODRUGS OF FENCAMFAMINE | Praxis Bioresearch, LLC (US) | 2018-07-25 | — | — | EP | disclosed |
| WO-2017048720-A1 | PRODRUGS OF FENCAMFAMINE | PRAXIS BIOSCIENCES, LLC (US) | 2017-03-23 | — | — | WO | disclosed |