SCHEMBL6053771

SCHEMBL6053771

c1ccc(C23CCC(CC2)C3)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.50
GRIN3B O60391 2/20 0.50
GRIN1 Q05586 2/20 0.50
GRIN2A Q12879 2/20 0.50
GRIN2B Q13224 2/20 0.50
GRIN2C Q14957 2/20 0.50
GRIN3A Q8TCU5 2/20 0.50
PNMT P11086 1/20 0.46
MAOB P27338 6/20 0.41
MAOA P21397 3/20 0.41
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9467531 0.87 LMNA (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8747758 0.85 PNMT (0.56) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9147001 0.82 GRIN2D (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL23071388 0.79 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9467542 0.78 KDM1A (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6939188 0.78 GRIN2D (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL181479 0.78 GRIN2D (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21409729 0.77 ALDH1A1 (0.67) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3049401 0.77 ESR2 (0.52)
SCHEMBL26006728 0.77 MEN1 (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890244-B2 Thermally decomposable polymer compositions incorporating thermally activated base generators SUMITOMO BAKELITE CO., LTD. (JP) 2018-02-13 US claimed
US-20150337081-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS PROMERUS, LLC (US) 2015-11-26 US claimed
US-9115300-B2 Thermally decomposable polymer compositions incorporating thermally activated base generators PROMERUS, LLC 2015-08-25 US claimed
US-20120318854-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS PROMERUS LLC (US) 2012-12-20 US claimed
WO-2012174384-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS PROMERUS LLC (US) 2012-12-20 WO claimed
US-5276211-A Grignard reaction, cyclization, organoleptic INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-01-04 US claimed
EP-1469004-B1 Method for preparing aminophosphines and aminophosphine oxides, intermediates therefor TAKASAGO PERFUMERY CO LTD (JP) 2006-06-14 EP disclosed
EP-1013658-B1 Aminophosphine-metal complex for asymmetric reactions TAKASAGO PERFUMERY CO LTD (JP) 2004-11-03 EP disclosed
EP-1469004-A1 Method for preparing aminophosphines and aminophosphine oxides, intermediates therefor Takasago International Corporation (JP) 2004-10-20 EP disclosed
US-6515156-B2 Stereoselective, efficient catalyst for synthesis of enantiomerically pure compounds; comprising compex of transition metal and aminophosphine ligand TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-02-04 US disclosed
US-6388130-B2 ALKALINE HYDROGEN PEROXIDE TO OXIDIZE 2-CYANO-2'-DIARYL PHOSPHINYL-1,1'-BINAPHTHYL TO OBTAIN A 2-AMIDO DERIVATIVE, REACTED WITH A METAL ALKOXIDE AND BROMINE IN AN ALCOHOL TO A 2-SEC-AMINO DERIVATIVE; TRANSITION METAL COMPLEX CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-14 US disclosed
US-20010047110-A1 Method for producing axial asymmetric compounds, intermediates for producing the same, complexes of transition metals with novel axial asymmetric compounds as the ligands, catalysts for asymmetric hydrogenation, and catalysts for forming asymmetric carbon-carbon bonds TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-29 US disclosed
US-6323353-B1 USED AS CATALYST FOR ASYMMETRIC HYDROGENATION OR CARBON-CARBON BOND TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-27 US disclosed
US-5461180-A Contacting norbornene and aromatic hydrocarbon with solid catalyst comprising porous crystalline material MOBIL OIL CORPORATION (US) 1995-10-24 US disclosed
US-5281576-A Perfumes with surfactants for detergents, fabric softener sheets INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-01-25 US disclosed
US-5281576-A Perfumes with surfactants for detergents, fabric softener sheets INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-01-25 US disclosed
US-5281576-A Perfumes with surfactants for detergents, fabric softener sheets INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-01-25 US disclosed
US-5276211-A Grignard reaction, cyclization, organoleptic INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-01-04 US disclosed
US-5276211-A Grignard reaction, cyclization, organoleptic INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-01-04 US disclosed
US-5276211-A Grignard reaction, cyclization, organoleptic INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010047110-A1 Method for producing axial asymmetric compounds, intermediates for producing the same, complexes of transition metals with novel axial asymmetric compounds as the ligands, catalysts for asymmetric hydrogenation, and catalysts for forming asymmetric carbon-carbon bonds CORO1C, AP3M1, ARL1 GRIN2D 809/4885GRIN3B 463/4885GRIN1 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.