Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 15/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892724 | 0.79 | SNCA (0.57) | SNCATRPV1MTNR1AMTNR1BHPGD | |
| SCHEMBL18643143 | 0.78 | SNCA (0.51) | SNCATRPV1MTNR1AMTNR1BHPGD | |
| SCHEMBL892673 | 0.77 | MTNR1A (0.64) | SNCAMTNR1AMTNR1BHPGDMMP9 | |
| SCHEMBL892542 | 0.75 | MTNR1A (0.61) | SNCAMTNR1AMTNR1BHPGDMMP9 | |
| SCHEMBL892422 | 0.74 | SNCA (0.57) | SNCAMTNR1AMTNR1BHPGD | |
| SCHEMBL892799 | 0.74 | MTNR1A (0.57) | SNCATRPV1MTNR1AMTNR1BHPGD | |
| SCHEMBL892816 | 0.74 | SNCA (0.58) | SNCAMTNR1AMTNR1BHPGDMMP9 | |
| SCHEMBL892488 | 0.74 | MTNR1A (0.65) | SNCAMTNR1AMTNR1BHPGDMMP9 | |
| SCHEMBL1704329 | 0.73 | MTNR1A (0.58) | SNCAMTNR1AMTNR1BHPGDMMP9 | |
| SCHEMBL891531 | 0.73 | MMP9 (0.61) | SNCAMTNR1AMTNR1BHPGDMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440550-B1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV LEUVEN KATH (BE) | 2017-03-15 | — | — | EP | disclosed |