SCHEMBL1864346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1856028	0.86	HSP90AA1 (0.50)	HSP90AA1HSP90AB1ERBB2
	SCHEMBL1860896	0.86	HSP90AA1 (0.50)	HSP90AA1HSP90AB1ERBB2HSP90B1TRAP1
	SCHEMBL1864350	0.81	HSP90AA1 (0.50)	HSP90AA1HSP90AB1ERBB2CRHBPCRHR2
	SCHEMBL1864503	0.81	HSP90AB1 (0.52)	HSP90AA1HSP90AB1MEN1KMT2A
	SCHEMBL1670297	0.81	HSP90AA1 (0.45)	HSP90AA1HSP90AB1ERBB2
	SCHEMBL1858046	0.79	HSP90AA1 (0.50)	HSP90AA1HSP90AB1ERBB2
	SCHEMBL24376789	0.75	HSP90AA1 (0.32)	HSP90AA1HSP90AB1ERBB2MAPT
	SCHEMBL1669217	0.75	ERBB2 (0.39)	HSP90AA1HSP90AB1ERBB2MAPT
	SCHEMBL1669717	0.74	HSP90AA1 (0.45)	HSP90AA1HSP90AB1CHEK2MEN1KMT2A
	SCHEMBL14222621	0.72	HSP90AA1 (0.41)	HSP90AA1HSP90AB1ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.