SCHEMBL1864503

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1669717	0.93	HSP90AA1 (0.45)	HSP90AB1HSP90AA1ALDH1A1HSD17B10MPO
	SCHEMBL14201605	0.88	MPO (0.47)	HSP90AB1HSP90AA1ALDH1A1HSD17B10MPO
	SCHEMBL1670392	0.83	PDE2A (0.37)	HSP90AB1HSP90AA1ALDH1A1HSD17B10MPO
	SCHEMBL4017663	0.83	HSP90AB1 (0.39)	HSP90AB1HSP90AA1ALDH1A1HSD17B10MPO
	SCHEMBL4017667	0.83	HSP90AB1 (0.39)	HSP90AB1HSP90AA1ALDH1A1HSD17B10MPO
	SCHEMBL1856028	0.81	HSP90AA1 (0.50)	HSP90AB1HSP90AA1
	SCHEMBL1864505	0.81	HSP90AB1 (0.50)	HSP90AB1HSP90AA1ALDH1A1HSD17B10MPO
	SCHEMBL1864346	0.81	HSP90AA1 (0.50)	HSP90AB1HSP90AA1MEN1KMT2A
	SCHEMBL1670138	0.81	TP53 (0.41)	ALDH1A1HSD17B10MPOADORA1LTB4R
	SCHEMBL20860826	0.80	ALDH1A1 (0.41)	HSP90AB1HSP90AA1ALDH1A1HSD17B10MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.