Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645210 | 0.95 | USP30 (0.46) | BRD4JAK2JAK1USP30BTK | |
| SCHEMBL15710604 | 0.87 | BTK (0.52) | BRD4JAK2JAK1USP30BTK | |
| SCHEMBL15143897 | 0.87 | BTK (0.52) | BRD4JAK2JAK1USP30BTK | |
| SCHEMBL23450710 | 0.87 | ALDH1A1 (0.41) | USP30BTKNR1D1STS | |
| SCHEMBL18290014 | 0.87 | ALDH1A1 (0.41) | USP30BTKNR1D1STS | |
| SCHEMBL30111806 | 0.87 | ALDH1A1 (0.41) | USP30BTKNR1D1STS | |
| SCHEMBL18644660 | 0.87 | BRD4 (0.51) | BRD4JAK2JAK1USP30BTK | |
| SCHEMBL18645207 | 0.84 | ACKR3 (0.46) | BRD4JAK2JAK1USP30ACHE | |
| SCHEMBL28233733 | 0.83 | JAK3 (0.38) | — | |
| SCHEMBL28233730 | 0.83 | JAK3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017041536-A1 | OXO-DIHYDROIMIDAZO PYRIDINE COMPOUND AND APPLICATIONS THEREOF | 东莞市真兴贝特医药技术有限公司 | 2017-03-16 | — | — | WO | disclosed |