Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644661 | 0.95 | BRD4 (0.47) | USP30BRD4JAK2JAK1ACHE | |
| SCHEMBL23450710 | 0.92 | ALDH1A1 (0.41) | USP30BTKNR1D1 | |
| SCHEMBL30111806 | 0.92 | ALDH1A1 (0.41) | USP30BTKNR1D1 | |
| SCHEMBL18290014 | 0.92 | ALDH1A1 (0.41) | USP30BTKNR1D1 | |
| SCHEMBL28233733 | 0.89 | JAK3 (0.38) | — | |
| SCHEMBL28233730 | 0.89 | JAK3 (0.38) | — | |
| SCHEMBL18645207 | 0.88 | ACKR3 (0.46) | USP30BRD4JAK2JAK1ACHE | |
| SCHEMBL16341281 | 0.88 | BTK (0.47) | USP30BRD4JAK2JAK1BTK | |
| SCHEMBL15156453 | 0.88 | BTK (0.47) | USP30BRD4JAK2JAK1BTK | |
| SCHEMBL18645214 | 0.87 | USP30 (0.48) | USP30BRD4JAK2JAK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017041536-A1 | OXO-DIHYDROIMIDAZO PYRIDINE COMPOUND AND APPLICATIONS THEREOF | 东莞市真兴贝特医药技术有限公司 | 2017-03-16 | — | — | WO | disclosed |