Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644689 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL18644682 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL4878415 | 0.75 | MAPT (0.40) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6114286 | 0.73 | MAPT (0.49) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| Bromide SCHEMBL6114352 | 0.72 | MAPT (0.48) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6114364 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6121242 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL16434197 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL10668490 | 0.67 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| Bromide SCHEMBL6114147 | 0.67 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617279-B1 | Imidazooxadiazole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-04-11 | — | — | US | disclosed |
| US-9598419-B1 | Imidazotriazine and imidazodiazine compounds | UNIVERSITE DE MONTREAL (CA) | 2017-03-21 | — | — | US | disclosed |