Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18645207 | 0.88 | ACKR3 (0.46) | ACKR3HTR6BCHEJAK2JAK1 | |
| SCHEMBL18645214 | 0.87 | USP30 (0.48) | HTR6BCHEJAK2JAK1USP30 | |
| SCHEMBL18644660 | 0.83 | BRD4 (0.51) | JAK2JAK1USP30BRD4ACHE | |
| SCHEMBL24041210 | 0.78 | ALDH1A1 (0.44) | USP30BRD4 | |
| SCHEMBL31437367 | 0.78 | ALDH1A1 (0.44) | USP30BRD4 | |
| SCHEMBL18289982 | 0.78 | ALDH1A1 (0.44) | USP30BRD4 | |
| SCHEMBL13875252 | 0.78 | ACKR3 (0.58) | ACKR3HTR6BCHEJAK2KDM1A | |
| SCHEMBL16320728 | 0.77 | BTK (0.51) | HTR6BCHEJAK2JAK1USP30 | |
| SCHEMBL16320727 | 0.77 | BTK (0.51) | HTR6BCHEJAK2JAK1USP30 | |
| SCHEMBL18285582 | 0.77 | PRMT5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753863-B | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017041536-A1 | OXO-DIHYDROIMIDAZO PYRIDINE COMPOUND AND APPLICATIONS THEREOF | 东莞市真兴贝特医药技术有限公司 | 2017-03-16 | — | — | WO | disclosed |