Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041210 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SLC2A1GFERMMP1MMP9 | |
| SCHEMBL18289982 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SLC2A1GFERMMP1MMP9 | |
| SCHEMBL24041207 | 0.97 | ALDH1A1 (0.41) | ALDH1A1SLC2A1GFERMMP1MMP9 | |
| SCHEMBL18645214 | 0.91 | USP30 (0.48) | USP30BRD4BTKANO1 | |
| SCHEMBL18285566 | 0.89 | GFER (0.42) | GFER | |
| SCHEMBL18285575 | 0.89 | GFER (0.42) | GFER | |
| SCHEMBL18290014 | 0.88 | ALDH1A1 (0.41) | ALDH1A1SLC2A1GFERMMP1MMP9 | |
| SCHEMBL23450710 | 0.88 | ALDH1A1 (0.41) | ALDH1A1SLC2A1GFERMMP1MMP9 | |
| SCHEMBL30111806 | 0.88 | ALDH1A1 (0.41) | ALDH1A1SLC2A1GFERMMP1MMP9 | |
| SCHEMBL29737087 | 0.87 | ALDH1A1 (0.40) | ALDH1A1SLC2A1MMP1MMP9SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119384411-A | Method for preparing tolmetinib | 普林斯匹亚生物制药公司 | 2025-01-28 | — | — | CN | disclosed |