SCHEMBL1864583

SCHEMBL1864583

CCCCCCCCc1ccc2c(c1CCCCCCCC)C(=O)NC2=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.42
CTSG P08311 2/20 0.42
TYR P14679 2/20 0.40
HSD17B10 Q99714 3/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
TYMP P19971 3/20 0.39
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX5 P09917 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28597691 0.94 ELANE (0.40) ELANECTSGTYRHSD17B10KDM4E
SCHEMBL27584887 0.88 ELANE (0.42) ELANECTSGTYRHSD17B10KDM4E
SCHEMBL27354265 0.84 KDM4E (0.44) ELANECTSGTYRHSD17B10KDM4E
SCHEMBL7640457 0.82 ELANE (0.56) ELANECTSGTYRHSD17B10KDM4E
SCHEMBL8967459 0.82 KDM4E (0.43) ELANECTSGTYRHSD17B10KDM4E
SCHEMBL28988954 0.81 ELANE (0.43) ELANECTSGTYRKDM4EALDH1A1
SCHEMBL30352889 0.81 ELANE (0.43) ELANECTSGTYRKDM4EALDH1A1
SCHEMBL10731776 0.80 ELANE (0.41) ELANECTSGKDM4EALDH1A1HPGD
SCHEMBL10725524 0.80 NR1H2 (0.49) ELANECTSGHSD17B10KDM4EALDH1A1
SCHEMBL10730459 0.80 NR1H2 (0.49) ELANECTSGHSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011054628-A1 ENHANCED PHOTO PROTECTION UNILEVER PLC (GB) 2011-05-12 WO disclosed
US-20110104082-A1 ENHANCED PHOTO PROTECTION CONOPCO, INC., D/B/A UNILEVER (US) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110104082-A1 ENHANCED PHOTO PROTECTION ERCC1, PCNA, CUTA ELANE 418/4885CTSG 1854/4885TYR 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.