SCHEMBL8967459

SCHEMBL8967459

CCCCCc1c(O)ccc2c1C(=O)NC2=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 4/20 0.43
HSD17B10 Q99714 3/20 0.43
GAA P10253 1/20 0.43
PKM P14618 1/20 0.42
ELANE P08246 2/20 0.40
CTSG P08311 2/20 0.40
TYR P14679 1/20 0.40
ALOX12 P18054 1/20 0.39
TYMP P19971 1/20 0.36
KAT8 Q9H7Z6 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27354265 0.98 KDM4E (0.44) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL1864583 0.82 ELANE (0.42) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL7640457 0.79 ELANE (0.56) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL28597691 0.78 ELANE (0.40) KDM4EALDH1A1HPGDHSD17B10PKM
SCHEMBL7024540 0.77 PARP1 (0.38) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL10624906 0.77 TYMP (0.41) KDM4EALDH1A1HPGDHSD17B10PKM
SCHEMBL2651667 0.77 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL27584887 0.76 ELANE (0.42) KDM4EALDH1A1HPGDHSD17B10ELANE
SCHEMBL72998 0.74 TYR (0.57) KDM4EALDH1A1HPGDHSD17B10TYR
SCHEMBL28343053 0.74 ELANE (0.55) KDM4EALDH1A1HPGDHSD17B10ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103497337-A Preparation method of polythioetherimide NINGBO INST MATERIALS TECHNOLOGY & ENG CAS 2014-01-08 CN disclosed
US-5530089-A Polysulfoneimides THE BOEING COMPANY (US) 1996-06-25 US disclosed
US-5268519-A Lightly crosslinked etherimide oligomers THE BOEING COMPANY (US) 1993-12-07 US disclosed
US-5175304-A Solvent resistant cured composite THE BOEING COMPANY (US) 1992-12-29 US disclosed
US-5144000-A Method for forming crosslinking polyetherimide oligomers THE BOEING COMPANY (US) 1992-09-01 US disclosed
US-4990624-A Intermediates anhydrides useful for synthesizing etherimides THE BOEING COMPANY (US) 1991-02-05 US disclosed
US-4981922-A Blended etherimide oligomers THE BOEING COMPANY (US) 1991-01-01 US disclosed
US-4958031-A ENDCAPPING POLYETHERIMIDE COPOLYMERS THE BOEING COMPANY (US) 1990-09-18 US disclosed
US-4851495-A Polyetherimide oligomer THE BOEING COMPANY (US) 1989-07-25 US disclosed
EP-0283636-A2 Polyetherimide oligomers and blends THE BOEING COMPANY (US) 1988-09-28 EP disclosed
US-4297474-A MOLDING MATERIALS; COATINGS; FILMS GENERAL ELECTRIC COMPANY (US) 1981-10-27 US disclosed
US-4297474-A MOLDING MATERIALS; COATINGS; FILMS GENERAL ELECTRIC COMPANY (US) 1981-10-27 US disclosed
US-4297474-A MOLDING MATERIALS; COATINGS; FILMS GENERAL ELECTRIC COMPANY (US) 1981-10-27 US disclosed