Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | PNLIP | P16233 | 2/20 | 0.46 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15596855 | 0.81 | CYP1A2 (0.47) | HSPB1HTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL641262 | 0.81 | MAPT (0.71) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL328386 | 0.81 | HTR2A (0.48) | HTR2ASLC6A4KCNH2KDM4EMEN1 | |
| SCHEMBL8298015 | 0.81 | HSPB1 (0.58) | HSPB1HTR2ASLC6A4KCNH2LMNA | |
| SCHEMBL4374841 | 0.81 | HSPB1 (0.58) | HSPB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9342871 | 0.81 | HSPB1 (0.58) | HSPB1MEN1KMT2AARPNLIP | |
| SCHEMBL4372913 | 0.81 | HSPB1 (0.58) | HSPB1HTR2ASLC6A4KCNH2LMNA | |
| SCHEMBL9339651 | 0.81 | HSPB1 (0.58) | HSPB1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14600351 | 0.80 | HSPB1 (0.54) | HSPB1HTR2ASLC6A4KCNH2LMNA | |
| SCHEMBL6157137 | 0.80 | HSPB1 (0.54) | HSPB1HTR2ASLC6A4KCNH2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247808-A1 | Heterocyclic Tec-Family Kinase Inhibitors | GB005, INC. | 2020-08-06 | — | — | US | disclosed |
| WO-2017041180-A1 | HETEROCYCLIC TEC-FAMILY KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247808-A1 | Heterocyclic Tec-Family Kinase Inhibitors | TEC, BTK, LCK | HSPB1 2608/4885HTR2A 4096/4885SLC6A4 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.