SCHEMBL18647

SCHEMBL18647

CC(C)(c1cc(Br)c(O)c(Br)c1)c1cc(Br)c(O)c(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 1.00
HSD17B10 Q99714 4/20 1.00
ALOX15 P16050 3/20 1.00
HIF1A Q16665 3/20 1.00
CYP3A4 P08684 3/20 1.00
ALOX12 P18054 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
ALDH1A1 P00352 2/20 1.00
HPGD P15428 2/20 1.00
CASP1 P29466 1/20 1.00
RECQL P46063 1/20 1.00
CHEK1 O14757 1/20 0.72
DAPK3 O43293 1/20 0.72
RET P07949 1/20 0.72
PDGFRB P09619 1/20 0.72
PIM1 P11309 1/20 0.72
PDGFRA P16234 1/20 0.72
KDR P35968 1/20 0.72
MAPK8 P45983 1/20 0.72
RPS6KA3 P51812 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5173922 1.00 TSHR (1.00) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL11567514 0.93 ALOX15 (0.86) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL5953176 0.91 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
Bicarbonate SCHEMBL11306999 0.91 ALOX15 (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL10013229 0.91 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL16383381 0.91 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
Hydroquinone SCHEMBL28245323 0.91 CYP3A4 (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
1,2-Dibromoethane SCHEMBL4910588 0.91 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL20762298 0.91 ALOX15 (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL901081 0.89 TSHR (0.79) TSHRHSD17B10ALOX15HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19794 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747302-A2 REPAIR AND OPTIMIZATION OF NANOCOMPOSITE MATERIALS Nanocore ApS (DK) 2026-05-27 EP claimed
CN-122091726-A Double-salt flame-retardant gel polymer electrolyte, in-situ preparation method and battery 2026-05-26 CN claimed
CN-122080582-A High-flame-retardance epoxy resin and preparation method thereof 2026-05-26 CN claimed
CN-116323801-B Polycarbonate composite composition and preparation method thereof LG CHEM, LTD. (KR) 2026-05-26 CN claimed
CN-122057385-A Hydrophilic efficient anti-pollution ultrafiltration membrane and preparation method thereof 长春工业大学 2026-05-19 CN claimed
CN-122036784-A Modified diallyl benzoxazine and bismaleimide resin and preparation method thereof 东华大学 2026-05-15 CN claimed
CN-122037698-A Flame-retardant strippable coating for ship outfitting protection, and preparation method and application thereof 中昊北方涂料工业研究设计院有限公司 2026-05-15 CN claimed
CN-224242748-U Tower for recycling tetrabromobisphenol A waste water solvent 天津长芦汉沽盐场有限责任公司 2026-05-15 CN claimed
CN-122037845-A High-toughness epoxy resin packaging adhesive, preparation method and application 北京康美特科技股份有限公司 2026-05-15 CN claimed
EP-4739403-A1 A FLUORINE-FREE FIRE EXTINGUISHING FORMULATION FOR ELECTROCHEMICAL ENERGY STORAGE AND CONVERSION SYSTEMS Uniteq S.A. (BE) 2026-05-13 EP claimed
US-4065436-A Thermoplastic polycarbonate moulding compositions with improved ease of mould release BAYER AKTIENGESELLSCHAFT (DT) 1977-12-27 US claimed
US-4064196-A BLEND OF COPOLYESTERS OF TEREPHTHALIC AND ISOPHTHALIC ACIDS WITH (1)BISPHENOL A AND (2)TETRACHLORO- OR TETRABROMO-BISPHENOL A UNITIKA LTD. (JA) 1977-12-20 US claimed
US-4046836-A FIREPROOFING, HYDROLYSIS RESISTANCE BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 US claimed
US-4041003-A Process for molding aromatic polycarbonates having perfluoroalkanesulphonic acid derivatives as mold release agents BAYER AKTIENGESELLSCHAFT (DT) 1977-08-09 US claimed
US-4026913-A COATINGS, ADHESIVES, MOLDING MATERIALS, FLEXIBILITY MITSUBISHI GAS CHEMICAL CO., LTD. (JA) 1977-05-31 US claimed
US-4025399-A ELECTRICAL, RECORDING LAYER WITH A CONDUCTIVE AGENT, A LEUCO BASE AND A PHENOLIC RESIN CANON KABUSHIKI KAISHA (JA) 1977-05-24 US claimed
US-4007150-A OR CYCLIMMONIUM SALTS OF PERFLUOROALKANESULPHONIC ACIDS AS MOLD RELEASE AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-08 US claimed
US-4005037-A Polycarbonate-polyvinyl chloride moulding compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US claimed
US-3966785-A Process for the preparation of bisphenol bischlorocarbonic acid esters BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed
US-3939117-A Process for producing a polyarylene ester SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-02-17 US claimed