SCHEMBL901081

SCHEMBL901081

CC(C)(c1cc(Br)c(N)c(Br)c1)c1cc(Br)c(O)c(Br)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.79
HSD17B10 Q99714 4/20 0.79
ALOX15 P16050 3/20 0.79
HIF1A Q16665 3/20 0.79
CYP3A4 P08684 3/20 0.79
ALOX12 P18054 2/20 0.79
TDP1 Q9NUW8 2/20 0.79
ALDH1A1 P00352 2/20 0.79
HPGD P15428 2/20 0.79
CASP1 P29466 1/20 0.79
RECQL P46063 1/20 0.79
CHEK1 O14757 1/20 0.60
DAPK3 O43293 1/20 0.60
RET P07949 1/20 0.60
PDGFRB P09619 1/20 0.60
PIM1 P11309 1/20 0.60
PDGFRA P16234 1/20 0.60
KDR P35968 1/20 0.60
MAPK8 P45983 1/20 0.60
RPS6KA3 P51812 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5173922 0.89 TSHR (1.00) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL18647 0.89 TSHR (1.00) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL6906660 0.89 ALOX15 (0.58) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL11567514 0.83 ALOX15 (0.86) TSHRHSD17B10ALOX15HIF1ACYP3A4
1,2-Dibromoethane SCHEMBL4910588 0.81 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL10013229 0.81 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL5953176 0.81 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL20762298 0.81 ALOX15 (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
SCHEMBL16383381 0.81 TSHR (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4
Bicarbonate SCHEMBL11306999 0.81 ALOX15 (0.83) TSHRHSD17B10ALOX15HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
CN-111801388-A High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2020-10-20 CN disclosed
WO-2020060257-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM 주식회사 엘지화학 2020-03-26 WO disclosed
EP-2726530-B1 HYBRID EPOXY RESIN ADDUCTS BLUE CUBE IP LLC (US) 2018-09-12 EP disclosed
EP-2621992-B1 EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF BLUE CUBE IP LLC (US) 2017-07-26 EP disclosed
US-9340702-B2 Coating compositions BLUE CUBE IP LLC (US) 2016-05-17 US disclosed
US-9284434-B2 Epoxy resin compositions BLUE CUBE IP LLC (US) 2016-03-15 US disclosed
EP-2621990-B1 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM BLUE CUBE IP LLC (US) 2016-02-24 EP disclosed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
US-4820798-A Cyanate functional maleimide thermosetting composition THE DOW CHEMICAL COMPANY (US) 1989-04-11 US disclosed
US-4820797-A ACETYLENIC COPOLYMERS THE DOW CHEMICAL COMPANY (US) 1989-04-11 US disclosed
EP-0291552-A1 Cyanate functional maleimides THE DOW CHEMICAL COMPANY (US) 1988-11-23 EP disclosed
US-4769440-A FLEXIBILITY THE DOW CHEMICAL COMPANY (US) 1988-09-06 US disclosed
US-4731426-A Polymerization product from cyanate functional maleimide THE DOW CHEMICAL COMPANY (US) 1988-03-15 US disclosed
US-4683276-A CASTING, LAMINATION, COATING THE DOW CHEMICAL COMPANY (US) 1987-07-28 US disclosed
US-4680378-A Cyanate functional maleimide and polyamine copolymer THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed