Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.47 |
| ▸ | TLR4 | O00206 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.37 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18471235 | 0.82 | BRD4 (0.50) | BRD4TLR4TLR8TLR9TLR7 | |
| SCHEMBL18518471 | 0.79 | ALDH1A1 (0.50) | BRD4TLR4TLR8TLR9TLR7 | |
| SCHEMBL15262095 | 0.79 | BRD4 (0.47) | BRD4TLR4TLR8TLR9TLR7 | |
| SCHEMBL18483006 | 0.77 | BRD4 (0.51) | BRD4TLR4TLR8TLR9TLR7 | |
| SCHEMBL15889927 | 0.75 | BRD4 (0.50) | BRD4TLR4TLR8TLR9TLR7 | |
| SCHEMBL16573986 | 0.72 | BRD4 (0.50) | BRD4CREBBPBMPR1BBMPR1AACVRL1 | |
| SCHEMBL24981713 | 0.72 | BRD4 (0.52) | BRD4TLR8CREBBPBMPR1BBMPR1A | |
| SCHEMBL1571625 | 0.72 | BRD4 (0.50) | BRD4TLR4TLR8TLR9TLR7 | |
| SCHEMBL19375140 | 0.72 | CREBBP (0.40) | BRD4TLR4TLR8TLR9TLR7 | |
| SCHEMBL13680661 | 0.69 | BRD4 (0.64) | BRD4CREBBPBMPR1BBMPR1AACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017042121-A1 | [{[2,3-DIHYDRO-1H-INDEN-1-YL]AMINO}-2H,3H-FURO[3,2-B]PYRIDIN-3-YL]ACETIC ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-16 | — | — | WO | disclosed |