Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14857200 | 1.00 | BDKRB1 (0.40) | BDKRB1CNR1 | |
| SCHEMBL2809653 | 0.91 | BDKRB1 (0.47) | BDKRB1CNR1 | |
| SCHEMBL2809091 | 0.91 | BDKRB1 (0.47) | BDKRB1CNR1 | |
| SCHEMBL186483 | 0.91 | BDKRB1 (0.47) | BDKRB1CNR1 | |
| SCHEMBL200796 | 0.84 | FAAH (0.33) | BDKRB1 | |
| SCHEMBL14856790 | 0.82 | BDKRB1 (0.40) | BDKRB1CNR1 | |
| SCHEMBL186548 | 0.82 | BDKRB1 (0.40) | BDKRB1CNR1 | |
| SCHEMBL14856788 | 0.82 | BDKRB1 (0.44) | BDKRB1 | |
| SCHEMBL14856785 | 0.82 | BDKRB1 (0.40) | BDKRB1CNR1 | |
| SCHEMBL14856663 | 0.82 | BDKRB1 (0.44) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |