Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24268941 | 0.89 | LMNA (0.38) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7770765 | 0.84 | LMNA (0.46) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL31453483 | 0.81 | LMNA (0.52) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL31453481 | 0.81 | LMNA (0.52) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL22730926 | 0.80 | ALDH1A1 (0.37) | LMNATDP1KDM4ESMN1; SMN2SIGMAR1 | |
| SCHEMBL31453488 | 0.78 | LMNA (0.50) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL31453480 | 0.78 | LMNA (0.50) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL6279880 | 0.76 | LMNA (0.41) | LMNA | |
| SCHEMBL5367349 | 0.76 | LMNA (0.48) | LMNACNR1ADRA1ATDP1KDM4E | |
| Water SCHEMBL11967853 | 0.76 | LMNA (0.48) | LMNACNR1ADRA1ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598361-B1 | Amino substituted acetamide derivative | KING SAUD UNIVERSITY (SA) | 2017-03-21 | — | — | US | disclosed |