SCHEMBL18650425

SCHEMBL18650425

O=NN1CCC(N2CCOCC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL3 Q96JM7 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.36
OPRL1 P41146 2/20 0.35
EPHX2 P34913 1/20 0.34
HSD11B1 P28845 1/20 0.34
ACHE P22303 1/20 0.34
HTR7 P34969 1/20 0.34
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
AOC3 Q16853 1/20 0.33
CBX7 O95931 1/20 0.33
CDYL2 Q8N8U2 1/20 0.33
CDYL Q9Y232 1/20 0.33
CDY1; CDY1B Q9Y6F8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Nitrosomorpholine SCHEMBL1578515 0.77
SCHEMBL26112778 0.77 SMN1; SMN2 (0.52) SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1KDM4E
SCHEMBL3168997 0.77
SCHEMBL26112782 0.77 SMN1; SMN2 (0.52) SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1KDM4E
N-Nitrosomorpholine SCHEMBL26048320 0.77
N-Nitrosomorpholine SCHEMBL27520827 0.77 CA12 (0.39) SMN1; SMN2L3MBTL1
SCHEMBL18650423 0.75 L3MBTL1 (0.38) L3MBTL3L3MBTL1ALDH1A1KDM4EACHE
SCHEMBL16877830 0.75
Ammonia Solution, Strong SCHEMBL4295582 0.74 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1KDM4E
SCHEMBL14862483 0.74 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017045648-A1 PREPARATION METHOD FOR DEUTERATED COMPOUND 正大天晴药业集团股份有限公司 2017-03-23 WO disclosed