Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436969 | 0.79 | L3MBTL1 (0.46) | L3MBTL1L3MBTL3ALDH1A1PIM1ACHE | |
| SCHEMBL23269640 | 0.77 | L3MBTL1 (0.44) | L3MBTL1L3MBTL3ALDH1A1PIM1ACHE | |
| SCHEMBL14307143 | 0.77 | L3MBTL1 (0.44) | L3MBTL1L3MBTL3ALDH1A1PIM1ACHE | |
| SCHEMBL22519024 | 0.77 | L3MBTL1 (0.41) | L3MBTL1L3MBTL3ALDH1A1PIM1ACHE | |
| SCHEMBL11623926 | 0.77 | — | — | |
| SCHEMBL81624 | 0.77 | L3MBTL1 (0.39) | L3MBTL1L3MBTL3ALDH1A1PIM1ACHE | |
| SCHEMBL26042916 | 0.77 | L3MBTL3 (0.47) | L3MBTL1L3MBTL3ALDH1A1PIM1ACHE | |
| SCHEMBL25171600 | 0.76 | POLB (0.40) | L3MBTL1L3MBTL3ALDH1A1KDM4EHRH3 | |
| SCHEMBL18650425 | 0.75 | SMN1; SMN2 (0.44) | L3MBTL1L3MBTL3ALDH1A1ACHEKDM4E | |
| SCHEMBL12772837 | 0.74 | L3MBTL3 (0.46) | L3MBTL1L3MBTL3ALDH1A1PIM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017045648-A1 | PREPARATION METHOD FOR DEUTERATED COMPOUND | 正大天晴药业集团股份有限公司 | 2017-03-23 | — | — | WO | disclosed |