Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.49 |
| ▸ | PREP | P48147 | 7/20 | 0.43 |
| ▸ | FAP | Q12884 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350270 | 0.87 | PREP (0.48) | DPP4PREPFAP | |
| SCHEMBL8350809 | 0.87 | POLB (0.49) | DPP4PREPFAP | |
| SCHEMBL18636997 | 0.87 | ACE (0.51) | DPP4PREPFAP | |
| SCHEMBL8350007 | 0.87 | ACE (0.51) | DPP4PREPFAP | |
| SCHEMBL2744394 | 0.86 | MEN1 (0.48) | DPP4PREPFAP | |
| SCHEMBL3763934 | 0.86 | MEN1 (0.48) | DPP4PREPFAP | |
| SCHEMBL8249414 | 0.86 | PREP (0.43) | DPP4PREPFAPHTR1AHTR7 | |
| SCHEMBL16470956 | 0.86 | DPP4 (0.47) | DPP4PREPFAPHTR1AHTR7 | |
| SCHEMBL30493625 | 0.85 | DPP4 (0.60) | DPP4PREPFAP | |
| SCHEMBL8131318 | 0.85 | EPHX1 (0.48) | DPP4PREPFAPHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE BAHAMAS LTD (BS) | 2017-03-22 | — | — | EP | disclosed |