Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15765599 | 0.88 | NOTUM (0.53) | TSHRLMNAMAPTXIAPALDH1A1 | |
| SCHEMBL10292602 | 0.88 | NOTUM (0.53) | TSHRLMNAMAPTXIAPALDH1A1 | |
| SCHEMBL3265355 | 0.80 | XIAP (0.52) | LMNAMAPTXIAPALDH1A1HTT | |
| SCHEMBL26620279 | 0.80 | TSHR (0.58) | MEN1KMT2ATSHRPOLBGAA | |
| SCHEMBL7814933 | 0.79 | XIAP (0.59) | XIAPACE | |
| SCHEMBL18653164 | 0.78 | XIAP (0.50) | XIAPACEDRD2DRD4 | |
| SCHEMBL15458270 | 0.78 | MAPT (0.72) | MEN1KMT2ATSHRLMNAMAPT | |
| SCHEMBL18595590 | 0.78 | MAPT (0.72) | MEN1KMT2ATSHRLMNAMAPT | |
| SCHEMBL11341941 | 0.77 | PDK1 (0.57) | MEN1KMT2ATSHRPOLBGAA | |
| SCHEMBL9470723 | 0.77 | MEN1 (0.60) | MEN1KMT2ATSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE BAHAMAS LTD (BS) | 2017-03-22 | — | — | EP | disclosed |