Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18654155 | 0.88 | KDM4E (0.60) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7196588 | 0.83 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL24677590 | 0.80 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29496935 | 0.80 | SMN1; SMN2 (0.62) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL18976884 | 0.80 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2039527 | 0.80 | SMN1; SMN2 (0.62) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL858806 | 0.78 | KDM4E (0.72) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL10801186 | 0.77 | ADRA1A (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL22122698 | 0.77 | KDM4E (0.53) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL2194879 | 0.77 | GRM5 (0.51) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3232490-B1 | ORGANIC LIGHT EMITTING DIODE COMPRISING AN ORGANIC SEMICONDUCTOR LAYER | NOVALED GMBH (DE) | 2021-03-17 | — | — | EP | disclosed |
| US-9972792-B2 | Electron transport layer and film having improved thermal stability | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170084847-A1 | ELECTRON TRANSPORT LAYER AND FILM HAVING IMPROVED THERMAL STABILITY | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2017-03-23 | — | — | US | disclosed |