Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.91 |
| ▸ | FLT3 | P36888 | 7/20 | 0.91 |
| ▸ | KDR | P35968 | 10/20 | 0.83 |
| ▸ | QPCT | Q16769 | 4/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655377 | 0.95 | GSK3B (0.91) | GSK3BFLT3KDRQPCT | |
| SCHEMBL9955798 | 0.95 | GSK3B (1.00) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL18655378 | 0.94 | GSK3B (0.86) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL9956127 | 0.91 | KDR (1.00) | GSK3BFLT3KDRQPCT | |
| SCHEMBL18655374 | 0.89 | GSK3B (0.87) | GSK3BFLT3KDRQPCT | |
| SCHEMBL19090416 | 0.86 | GSK3B (0.82) | GSK3BFLT3KDRQPCT | |
| SCHEMBL10069744 | 0.84 | GSK3B (1.00) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL18655372 | 0.83 | GSK3B (0.80) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL19070784 | 0.81 | GSK3B (0.81) | GSK3BFLT3KDRQPCT | |
| SCHEMBL10070114 | 0.81 | GSK3B (0.73) | GSK3BFLT3KDRQPCTCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655359-B1 | CONJUGATED 3-(INDOLYL)- AND 3-(AZAINDOLYL)-4-ARYLMALEIMIDE COMPOUNDS AND THEIR USE IN TUMOR TREATMENT | Johannes-Gutenberg-Universität Mainz (DE) | 2017-03-22 | — | — | EP | disclosed |