Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ATM | Q13315 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | GLA | P06280 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | CASP1 | P29466 | 4/20 | 0.50 |
| ▸ | CASP7 | P55210 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655467 | 0.82 | ALDH1A1 (0.67) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL11584450 | 0.78 | ALDH1A1 (0.67) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL2195842 | 0.77 | ALDH1A1 (0.68) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL20796624 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL29952780 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL12509949 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL29493311 | 0.77 | ALDH1A1 (0.68) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL16098880 | 0.76 | ALDH1A1 (0.54) | ALDH1A1NPSR1MAPTATMHPGD | |
| SCHEMBL18655469 | 0.74 | PRKDC (0.36) | ALDH1A1NPSR1MAPTHPGDMEN1 | |
| SCHEMBL18113715 | 0.74 | MAPT (0.75) | ALDH1A1NPSR1MAPTATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004229-B | Coumarin derivative for specifically identifying and distinguishing DNA (deoxyribonucleic acid) and RNA (ribonucleic acid), and preparation method and application thereof | 郑州大学 | 2021-02-05 | — | — | CN | claimed |
| US-10222390-B2 | Near-infrared fluorescent sensors for biological amines | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170082645-A1 | NEAR-INFRARED FLUORESCENT SENSORS FOR BIOLOGICAL AMINES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2017-03-23 | — | — | US | disclosed |
| US-20170082645-A1 | NEAR-INFRARED FLUORESCENT SENSORS FOR BIOLOGICAL AMINES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2017-03-23 | — | — | US | disclosed |