Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20796625 | 0.86 | PSMB8 (0.40) | PRKDCPSMB8MAOBMAOAALDH1A1 | |
| SCHEMBL20796392 | 0.82 | KDM4E (0.36) | PRKDCPSMB8MAOBMAOAALDH1A1 | |
| SCHEMBL18659846 | 0.78 | PRKDC (0.45) | PRKDCPSMB8MAOBMAOAALDH1A1 | |
| SCHEMBL18659700 | 0.77 | ALDH2 (0.35) | MAOBALDH1A1NPSR1KDM4EMAPT | |
| SCHEMBL18659845 | 0.77 | ESR1 (0.32) | ALDH1A1NPSR1 | |
| SCHEMBL18655468 | 0.74 | ALDH1A1 (0.57) | MAOBALDH1A1NPSR1KDM4EMAPT | |
| SCHEMBL20796623 | 0.74 | ALDH1A1 (0.32) | ALDH1A1NPSR1 | |
| SCHEMBL20314437 | 0.62 | MEN1 (0.55) | PRKDCALDH1A1KDM4EMAPTGAA | |
| SCHEMBL5439109 | 0.61 | ERAP1 (0.64) | PSMB8MAOBMAOAALDH1A1NPSR1 | |
| SCHEMBL12732259 | 0.60 | NR3C1 (0.34) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222390-B2 | Near-infrared fluorescent sensors for biological amines | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170082645-A1 | NEAR-INFRARED FLUORESCENT SENSORS FOR BIOLOGICAL AMINES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2017-03-23 | — | — | US | disclosed |
| US-20170082645-A1 | NEAR-INFRARED FLUORESCENT SENSORS FOR BIOLOGICAL AMINES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2017-03-23 | — | — | US | disclosed |