Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655466 | 0.95 | GPR35 (0.45) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL18655496 | 0.80 | GPR35 (0.42) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL991721 | 0.75 | GPR35 (0.51) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL336915 | 0.75 | GPR35 (0.51) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL861104 | 0.75 | GPR35 (0.51) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL995654 | 0.75 | GPR35 (0.51) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL3842694 | 0.75 | GPR35 (0.51) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL3372174 | 0.75 | GPR35 (0.51) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL18655326 | 0.75 | GPR35 (0.43) | GPR35KCNH2ALDH1A1TP53CYP3A4 | |
| SCHEMBL14889177 | 0.75 | GPR35 (0.37) | GPR35KCNH2TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046554-A1 | ANTHRATHIOPHENE DERIVATIVES WITH TRANSVERSE SOLUBILISING UNITS AND THEIR APPLICATIONS AS ORGANIC SEMICONDUCTORS | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2017-03-23 | — | — | WO | disclosed |