SCHEMBL861104

SCHEMBL861104

CCCCCCCCc1c2ccsc2c(CCCCCCCC)c2ccsc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 5/20 0.51
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 3/20 0.37
ESR1 P03372 2/20 0.37
ADRA2A P08913 2/20 0.37
ADORA3 P0DMS8 2/20 0.37
TACR2 P21452 2/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
KCNH2 Q12809 2/20 0.37
TP53 P04637 2/20 0.37
CYP3A4 P08684 2/20 0.37
HIF1A Q16665 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
SHBG P04278 1/20 0.37
HSPD1 P10809 1/20 0.37
ADRB3 P13945 1/20 0.37
HTR2C P28335 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL336915 1.00 GPR35 (0.51) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL995654 1.00 GPR35 (0.51) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL3842694 1.00 GPR35 (0.51) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL12287573 0.93 GPR35 (0.47) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL3372174 0.92 GPR35 (0.51) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL991721 0.92 GPR35 (0.51) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL3370849 0.90 GPR35 (0.49) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL31498432 0.90 GPR35 (0.45) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL13872964 0.87 GPR35 (0.46) GPR35ALDH1A1HSD17B10ESR1ADRA2A
SCHEMBL13592429 0.87 GPR35 (0.46) GPR35ALDH1A1HSD17B10ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3243818-B1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2021-02-17 EP disclosed
US-10158079-B2 Polymers of benzodithiophene and their use as organic semiconductors MERCK PATENT GMBH (DE) 2018-12-18 US disclosed
EP-3243818-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2017-11-15 EP disclosed
EP-2560965-B1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2017-06-14 EP disclosed
US-20150207076-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2015-07-23 US disclosed
US-20150207076-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2015-07-23 US disclosed
US-9029499-B2 Semiconducting polymers UNIVERSITY OF CHICAGO (US) 2015-05-12 US disclosed
EP-2432817-B1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES RAYNERGY TEK INC (TW) 2015-02-11 EP disclosed
US-20140235817-A1 SEMICONDUCTING POLYMERS UNIVERSITY OF CHICAGO (US) 2014-08-21 US disclosed
US-8748739-B2 Conjugated polymers and their use in optoelectronic devices POLYERA CORPORATION (US) 2014-06-10 US disclosed
US-20130043434-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-02-21 US disclosed
US-20130043434-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-02-21 US disclosed
US-8334456-B2 Conjugated polymers and their use in optoelectronic devices POLYERA CORPORATION (US) 2012-12-18 US disclosed
US-8334456-B2 Conjugated polymers and their use in optoelectronic devices POLYERA CORPORATION (US) 2012-12-18 US disclosed
EP-2432817-A1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES Polyera Corporation (US) 2012-03-28 EP disclosed
WO-2011131280-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-10-27 WO disclosed
US-20110124822-A1 SEMICONDUCTING POLYMERS NATIONAL SCIENCE FOUNDATION 2011-05-26 US disclosed
US-20100307594-A1 Conjugated Polymers and Their Use in Optoelectronic Devices RAYNERGY TEK INC. (TW) 2010-12-09 US disclosed
US-20100307594-A1 Conjugated Polymers and Their Use in Optoelectronic Devices RAYNERGY TEK INC. (TW) 2010-12-09 US disclosed
WO-2010135701-A1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES POLYERA CORPORATION (US) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150207076-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS TST, TPST2, PPOX GPR35 4213/4885ALDH1A1 2396/4885HSD17B10 2686/4885
US-20130043434-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS TST, TPST2, PPOX GPR35 4213/4885ALDH1A1 2396/4885HSD17B10 2686/4885
US-10158079-B2 Polymers of benzodithiophene and their use as organic semiconductors TST, TPST2, PPOX GPR35 4213/4885ALDH1A1 2396/4885HSD17B10 2686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.