Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655825 | 0.89 | — | — | |
| SCHEMBL20457120 | 0.84 | MEN1 (0.36) | MEN1KMT2AMAPTHTT | |
| SCHEMBL2394227 | 0.80 | — | — | |
| SCHEMBL18655827 | 0.78 | — | — | |
| SCHEMBL9047154 | 0.77 | NPC1 (0.35) | HTT | |
| SCHEMBL4374691 | 0.76 | MEN1 (0.32) | MEN1KMT2AGAA | |
| SCHEMBL6175632 | 0.71 | — | — | |
| SCHEMBL18655829 | 0.70 | — | — | |
| SCHEMBL10744284 | 0.68 | MEN1 (0.37) | MEN1KMT2AGAAMAPTHTT | |
| SCHEMBL502245 | 0.68 | MEN1 (0.37) | MEN1KMT2AGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081360-A1 | Chemically Modifying Peptides | THE UNIVERSITY OF DURHAM (GB) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081360-A1 | Chemically Modifying Peptides | PTMS, DNPEP, NGLY1 | MEN1 67/4885KMT2A 1865/4885GAA 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.