SCHEMBL502245

SCHEMBL502245

Fc1nc(F)c(Cl)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8519416 0.87 MEN1 (0.33) MEN1KMT2AGAA
SCHEMBL282140 0.87 MEN1 (0.35) MEN1KMT2AGAAMAPTHTT
SCHEMBL9513607 0.84 MEN1 (0.34) MEN1KMT2AGAA
SCHEMBL10744284 0.81 MEN1 (0.37) MEN1KMT2AGAAMAPTHTT
SCHEMBL7028015 0.80 MEN1 (0.36) MEN1KMT2AGAAMAPTHTT
SCHEMBL7034473 0.79
SCHEMBL9787166 0.76 MEN1 (0.32) MEN1KMT2AGAA
SCHEMBL188694 0.75 MEN1 (0.41) MEN1KMT2AMAPTHTT
SCHEMBL4852202 0.75 MEN1 (0.42) MEN1KMT2AGAAMAPTHTT
SCHEMBL10870412 0.75 MEN1 (0.31) MEN1KMT2AGAAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3149020-A2 CHEMICALLY MODIFYING PEPTIDES The University of Durham (GB) 2017-04-05 EP claimed
WO-2015181544-A2 CHEMICALLY MODIFYING PEPTIDES THE UNIVERSITY OF DURHAM (GB) 2015-12-03 WO claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
US-4542221-A Exchanging fluorine for chlorine in a chlorinated pyridine with an alkali metal fluoride THE DOW CHEMICAL COMPANY (US) 1985-09-17 US claimed
EP-4363409-B1 METHOD FOR THE PRODUCTION OF ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2025-06-11 EP disclosed
US-20240308970-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2024-09-19 US disclosed
EP-4363409-A1 METHOD FOR PRODUCING ALKYLENE OXIDES Covestro Deutschland AG (DE) 2024-05-08 EP disclosed
CN-117929444-A Method, system and related equipment for measuring Hamiltonian amount of sample 深圳量旋科技有限公司 2024-04-26 CN disclosed
US-20240067621-A1 POLYFLUORINATED CANNABINOID AND CANNABINOID-LIKE COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF WEAVER JIMMIE D (US) 2024-02-29 US disclosed
EP-4298096-A1 POLYFLUORINATED DICYCLIC COMPOUNDS AND METHODS OF SYNTHESIS THEREOF The Board of Regents for the Oklahoma Agricultural And Mechanical Colleges (US) 2024-01-03 EP disclosed
WO-2023274993-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2023-01-05 WO disclosed
EP-0270221-A1 Method of preparation of 3,5-dichloro-2,4,6-trifluoropyridine DOWELANCO (US) 1988-06-08 EP disclosed
US-4746744-A Method of preparation of 3,5-dichloro-2,4,6-trifluoropyridine THE DOW CHEMICAL COMPANY (US) 1988-05-24 US disclosed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US disclosed
EP-0044890-B1 PROCESS FOR PREPARING FLUOROPYRIDINE COMPOUNDS DOW CHEMICAL COMPANY LIMITED (GB) 1987-01-28 EP disclosed
EP-0192287-A2 Process for the preparation of fluorinated pyridines SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-08-27 EP disclosed
US-4542221-A Exchanging fluorine for chlorine in a chlorinated pyridine with an alkali metal fluoride THE DOW CHEMICAL COMPANY (US) 1985-09-17 US disclosed
EP-0120575-A1 Organic fluorine compounds Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1984-10-03 EP disclosed
EP-0044890-A1 Process for preparing fluoropyridine compounds DOW CHEMICAL COMPANY LIMITED (GB) 1982-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067621-A1 POLYFLUORINATED CANNABINOID AND CANNABINOID-LIKE COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF CNR2, CNR1, FAAH MEN1 3122/4885KMT2A 1505/4885GAA 2419/4885
US-20240308970-A1 METHOD FOR PRODUCING ALKYLENE OXIDES AOC2, SCO2, AOC3 MEN1 3047/4885KMT2A 2604/4885GAA 3180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.