Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19389920 | 0.84 | ATM (0.40) | ATMMEN1KMT2AGLAL3MBTL1 | |
| SCHEMBL29105869 | 0.82 | ATM (0.51) | ATMMEN1KMT2AGLAL3MBTL1 | |
| SCHEMBL24938947 | 0.82 | ATM (0.51) | ATMMEN1KMT2AGLAL3MBTL1 | |
| SCHEMBL29496240 | 0.81 | MEN1 (0.40) | SRCATMGABRA1GABRG2GABRB3 | |
| SCHEMBL19390106 | 0.81 | NR1H2 (0.39) | ATMMEN1KMT2ADDB1CRBN | |
| SCHEMBL3734172 | 0.80 | GLA (0.39) | SRCKMT2AGLANFKB1NFKB2 | |
| SCHEMBL15288010 | 0.80 | FKBP1A (0.41) | ATMMEN1KMT2AGLANFKB1 | |
| SCHEMBL16749567 | 0.80 | FKBP1A (0.41) | ATMMEN1KMT2AGLANFKB1 | |
| SCHEMBL15288011 | 0.80 | FKBP1A (0.41) | ATMMEN1KMT2AGLANFKB1 | |
| SCHEMBL1900990 | 0.79 | GABRA1 (0.46) | ATMGABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017045510-A1 | Β-LACTAMASE INHIBITOR AND APPLICATION THEREOF | 山东轩竹医药科技有限公司 | 2017-03-23 | — | — | WO | disclosed |