⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13992018 | 0.87 | — | — | |
| SCHEMBL16587955 | 0.86 | IDUA (0.30) | — | |
| SCHEMBL28766375 | 0.84 | IDUA (0.33) | — | |
| SCHEMBL25756358 | 0.79 | TSHR (0.36) | — | |
| SCHEMBL25756224 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL23765754 | 0.78 | MEN1 (0.41) | — | |
| SCHEMBL19872804 | 0.77 | — | — | |
| SCHEMBL17318111 | 0.76 | CA2 (0.32) | — | |
| SCHEMBL16587606 | 0.75 | — | — | |
| SCHEMBL25457443 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112855-A1 | LIPID COMPOUND AND THE COMPOSITION THEREOF | Guangzhou Ribobio Co., Ltd (CN) | 2022-06-02 | — | — | WO | disclosed |
| US-11141495-B2 | MRI imaging of amyloid plaque using liposomes | TEXAS CHILDREN'S HOSPITAL (US) | 2021-10-12 | — | — | US | disclosed |
| US-9744251-B2 | MRI imaging of amyloid plaque using liposomes | Alzeca Biosciences, LLC | 2017-08-29 | — | — | US | disclosed |
| US-20170080111-A1 | MRI IMAGING OF AMYLOID PLAQUE USING LIPOSOMES | Alzeca Biosciences, LLC | 2017-03-23 | — | — | US | disclosed |