Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997373 | 0.86 | SLC6A4 (0.64) | L3MBTL1RAB9AMAPTNPSR1FFAR1 | |
| SCHEMBL5024165 | 0.84 | L3MBTL1 (0.71) | L3MBTL1RAB9AMAPTNPSR1FFAR1 | |
| SCHEMBL12261813 | 0.84 | KDM4E (0.46) | RAB9AMAPTNPSR1LMNANTRK1 | |
| SCHEMBL13997359 | 0.83 | L3MBTL1 (0.47) | L3MBTL1RAB9AMAPTNPSR1FFAR1 | |
| SCHEMBL4522930 | 0.83 | L3MBTL1 (0.56) | L3MBTL1RAB9AMAPTNPSR1SLC6A4 | |
| SCHEMBL13997375 | 0.83 | HTR2A (0.59) | L3MBTL1RAB9AMAPTFFAR1SLC6A4 | |
| SCHEMBL19951345 | 0.81 | FFAR1 (0.57) | L3MBTL1RAB9AMAPTFFAR1MRGPRX4 | |
| SCHEMBL11385841 | 0.81 | L3MBTL1 (0.71) | L3MBTL1RAB9AMAPTNPSR1FFAR1 | |
| SCHEMBL4509569 | 0.81 | THRB (0.48) | L3MBTL1RAB9AMAPTNPSR1SCN8A | |
| SCHEMBL4520270 | 0.81 | TTR (0.56) | L3MBTL1RAB9AMAPTNPSR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144303-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |