Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827993 | 0.82 | TSHR (0.71) | FFAR4PPARGFFAR1L3MBTL1TSHR | |
| SCHEMBL18656075 | 0.81 | PPARD (0.44) | PPARGFFAR1L3MBTL1MCL1PPARA | |
| SCHEMBL7827991 | 0.80 | MCL1 (0.69) | FFAR4FFAR1MCL1 | |
| SCHEMBL6883728 | 0.80 | L3MBTL1 (0.82) | FFAR4PPARGFFAR1L3MBTL1TSHR | |
| SCHEMBL29700092 | 0.78 | FFAR4 (0.62) | FFAR4FFAR1SCN5ACYP2C9 | |
| SCHEMBL116455 | 0.78 | FFAR4 (0.62) | FFAR4FFAR1SCN5ACYP2C9 | |
| SCHEMBL21533581 | 0.77 | FFAR4 (0.58) | FFAR4PPARGFFAR1L3MBTL1TSHR | |
| SCHEMBL30888680 | 0.76 | LMNA (0.54) | FFAR4PPARGFFAR1L3MBTL1TSHR | |
| SCHEMBL11428548 | 0.76 | HTR2A (0.50) | L3MBTL1CYP2C9KCNH2 | |
| SCHEMBL14570559 | 0.76 | TSHR (0.62) | FFAR4PPARGFFAR1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144303-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |