SCHEMBL1865628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1863824	0.95	TLR4 (0.43)	TLR4SMN1; SMN2NLRP3CYP2C9MEN1
	SCHEMBL1859826	0.94	TLR4 (0.46)	TLR4SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL1866883	0.90	TLR4 (0.47)	TLR4CYP2C9MEN1KMT2AMAPT
	SCHEMBL1862805	0.90	TLR4 (0.50)	TLR4SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL1866369	0.89	TLR4 (0.46)	TLR4SMN1; SMN2NLRP3MEN1KMT2A
	SCHEMBL1861989	0.89	TLR4 (0.52)	TLR4SMN1; SMN2MAPTKDM4EHSD17B10
	SCHEMBL1862876	0.89	TLR4 (0.39)	TLR4SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL1865497	0.85	TLR4 (0.46)	TLR4SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL1870302	0.85	TLR4 (0.40)	TLR4SMN1; SMN2CYP2C9MEN1KMT2A
	SCHEMBL1862680	0.85	TLR4 (0.45)	TLR4SMN1; SMN2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.