SCHEMBL1862805

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1866883	0.93	TLR4 (0.47)	TLR4MAPTTSHRGAAKDM4E
	SCHEMBL1861053	0.90	TLR4 (0.43)	TLR4MAPTTSHRGAAKDM4E
	SCHEMBL1866081	0.90	TLR4 (0.42)	TLR4TSHRGAAKDM4ESMN1; SMN2
	SCHEMBL1865628	0.90	TLR4 (0.45)	TLR4MAPTTSHRGAAKDM4E
	SCHEMBL1872614	0.89	TLR4 (0.51)	TLR4MAPTTSHRGAAKDM4E
	SCHEMBL1861968	0.89	TLR4 (0.55)	TLR4MAPTKDM4ELMNAALDH1A1
	SCHEMBL1864530	0.89	TLR4 (0.55)	TLR4MAPTTSHRALDH1A1NPC1
	SCHEMBL1867851	0.89	TLR4 (0.42)	TLR4TSHRGAAKDM4ESMN1; SMN2
	SCHEMBL1859769	0.89	TLR4 (0.42)	TLR4TSHRGAAKDM4ESMN1; SMN2
	SCHEMBL1866325	0.89	TLR4 (0.49)	TLR4MAPTTSHRKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.