Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 9/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865731 | 1.00 | KLKB1 (0.45) | KLKB1HTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1870117 | 0.92 | BRAF (0.47) | KLKB1BRAFKLK1MASP2FLT3 | |
| SCHEMBL1861630 | 0.92 | BRAF (0.45) | KLKB1BRAFKLK1MASP2FLT3 | |
| SCHEMBL1870114 | 0.92 | BRAF (0.47) | KLKB1BRAFKLK1MASP2FLT3 | |
| SCHEMBL1861627 | 0.92 | BRAF (0.45) | KLKB1BRAFKLK1MASP2FLT3 | |
| SCHEMBL1867170 | 0.90 | BRAF (0.42) | KLKB1BRAFMASP2FLT3NAMPT | |
| SCHEMBL1867173 | 0.90 | BRAF (0.42) | KLKB1BRAFMASP2FLT3NAMPT | |
| SCHEMBL1863379 | 0.89 | BRAF (0.47) | KLKB1BRAFKLK1MASP2FLT3 | |
| SCHEMBL1867774 | 0.89 | BRAF (0.47) | KLKB1BRAFKLK1MASP2FLT3 | |
| SCHEMBL1863382 | 0.89 | BRAF (0.47) | KLKB1BRAFKLK1MASP2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |